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A method to measure visual field sensitivity at the edges of glaucomatous scotomata

机译:一种测量青光眼幕旁边缘视野敏感度的方法

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Purpose. To develop and evaluate a method to map glaucomatous visual field (VF) damage by allocating additional test points to the standard 6° interval VF test pattern, considering the distribution of VF scotomata. Methods. Subjects comprised 22 glaucomatous patients. Gradients of sensitivity were calculated for "squares" of test points in a patient's 24-2/30-2 VF results, so that the edges of scotomata could be identified where gradients were steep. Next, 10 new VF points were placed in these locations for each patient. Each patient's VF was then measured using this novel test grid (52 standard 24-2 test points and 10 additional points examined concurrently) on two separate occasions. The absolute difference between the measured sensitivity at each new additional test point and the average of the sensitivities of its surrounding four test points was calculated (Δave). The intra- and intervisit reproducibility of the additional test points' thresholds was calculated. Finally, fluctuation of overall VF damage was estimated using the intraclass correlation coefficient (ICC) and the coefficient of variation (CV). Results. The average of the sensitivities (Δave) increased as the gradient of the plane steepened, whereas the reproducibility of the additional test points' thresholds remained stable. ICC was significantly higher and CV was significantly lower for the novel test grid compared with the standard 24-2 test pattern. Conclusions. It may be advantageous to increase the density of VF test points where there are large local differences in VF sensitivity. These additional measurements may result in more reproducible and well-defined estimates of scotomata.
机译:目的。通过分配额外的测试点到标准的6°间隔VF测试图来考虑VF盲孔的分布,以开发和评估映射青光眼视野(VF)损伤的方法。方法。受试者包括22名青光眼患者。计算患者的24-2 / 30-2 VF结果中测试点“平方”的灵敏度梯度,以便可以在梯度较陡的地方识别盲孔的边缘。接下来,为每个患者在这些位置放置10个新的VF点。然后,在两个不同的场合使用这种新颖的测试网格(52个标准的24-2测试点和同时检查的10个其他点)测量每个患者的VF。计算在每个新的附加测试点处测得的灵敏度与其周围四个测试点的灵敏度平均值之间的绝对差(Δave)。计算了其他测试点阈值的内部和内部重现性。最后,使用组内相关系数(ICC)和变异系数(CV)估算整个VF损伤的波动。结果。灵敏度的平均值(Δave)随着平面的坡度变陡而增加,而其他测试点阈值的可重复性保持稳定。与标准24-2测试模式相比,新型测试网格的ICC显着更高,CV显着更低。结论。在VF灵敏度存在较大局部差异的情况下,增加VF测试点的密度可能是有利的。这些额外的测量结果可能会产生更多可重复且定义明确的defined估计。

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