Transition-Metal-Free Intramolecular Carbene Aromatic Substitution/Buchner Reaction: Synthesis of Fluorenes and [6,5,7]Benzo-fused Rings

摘要

Intramolecular aromatic substitution and Buchner reaction have been established as powerful methods for the construction of polycyclic compounds. These reactions are traditionally catalyzed by Rh-II catalysts with -diazocarbonyl compounds as the substrates. Herein a transition-metal-free intramolecular aromatic substitution/Buchner reaction is presented. These reactions use readily available N-tosylhydrazones as the diazo compound precursors and show wide substrate scope.