Directed Animation of Non-Acidic Arene C-H Bonds by a Copper-Silver Catalytic System

摘要

New methods for direct arylation, alkylation, and oxygenation of C(sp2)-H bonds in directing-group-containing benzenes have resulted in efficient synthetic routes to function-alized arenes. In contrast, direct animation reactions that do not proceed through nitrenoid intermediates are relatively rare. In most cases, palladium catalysis is used for amination-s. Furthermore, the majority of publications describe intramolecular C-N bond formation.