Substrate-Assisted Assembly of Interconnected Single-Duplex DNA Nanostructures

摘要

A general methodology for the creation of arbitrary shapes and patterns is one of the ultimate goals of nanostructural studies. One approach to this goal is the formation of building blocks that cover nearly all varieties of shapes. Recently, DNA has become known as a new material for nanoscale structures. By using the Watson-Crick complementarity of the double helix, we can design 2D and 3D DNA nanostructures and self-assemble them in solution. The basic methodology of this structural DNA nanotechnology is to design a rigid 'motif that comprises several DNA junctions and can be used as a building block.