Preparation and characterization of excellent antibacterial TiO2/N-halamines nanoparticles

摘要

In this work, N-halamine siloxanes poly[5,5-dimethy1-3-(3'-triethoxysilylpropyl)hydantoin] (PSPH) was synthesized, and PSPH/TiO2 nanocomposites (NCs) were prepared by a sol-gel process at a low temperature (about 100 degrees C). Chlorinated PSPH/TiO2 NCs (CI-PSPH/TiO2 NCs) were prepared by a chlorination reaction of PSPH/TiO2 NCs in diluted sodium hypochlorite solutions. The structural characteristics of these as-prepared PSPH/TiO2 NCs were determined by fourier transform infra-red (FTIR), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD),C-13 and Si-29 solid-state nuclear magnetic resonance (C-13 NMR, Si-29 NMR). The characterization of these as-prepared organic-inorganic hybrid materials by FTIR, XPS and Si-29 NMR showed that Ti-O-Si bonds between nano-TiO2 and PSPH were formed. The CI-PSPH/TiO2 NCs showed great antibacterial properties against Staphylococcus aureus (ATCC 6538) and Escherichia coli 0157:H7 (ATCC 43895) as well. The N-Cl bond of CI-PSPH/TiO2 NCs showed outstanding stability under UV light irradiation. The results of in vitro cell viability test showed that the PSPH/TiO2 NCs have excellent cytocompatibility to mammalian cells. (C) 2016 Elsevier B.V. All rights reserved.