Squamous Cell Hyperplasia

摘要

Sharply demarcated areas of erythema had been present on a 59-year-old woman's vulva and perineal and perianal regions for 2 years. She reported that the areas were intensely pruritic, especially when touched with anything, such as a washcloth during bathing. The itching was more severe than that associated with any episode of candidal vagini-tis she had ever experienced. At times the areas would become white and scaly. She had tried antifungal creams, over-the-counter corticosteroid creams, and various herbal remedies with no response.An elliptical incisional biopsy was done through the edge of the lesion on the right vulva. Histopathologic examination revealed squamous cell hyperplasia with mild hyperkeratosis, minimal chronic inflammation, and reactive squamous atypia; there was no evidence of dysplasia or malignancy.