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Sensitivity analysis for nonrandom dropout: A local influence approach

机译:非随机辍学的敏感性分析:一种局部影响方法

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Diggle and Kenward (1994, Applied Statistics 43, 49-93) proposed a selection model for continuous longitudinal data subject to nonrandom dropout. It has provoked a large debate about the role for such models. The original enthusiasm was followed by skepticism about the strong but untestable assumptions on which this type of model invariably rests. Since then, the view has emerged that these models should ideally be made part of a sensitivity analysis. This paper presents a formal and flexible approach to such a sensitivity assessment based on local influence (Cook, 1986, Journal of the Royal Statistical Society, Series B 48, 133-169). The influence of perturbing a missing-at-random dropout model in the direction of nonrandom dropout is explored. The method is applied to data from a randomized experiment on the inhibition of testosterone production in rats. [References: 21]
机译:Diggle和Kenward(1994,Applied Statistics 43,49-93)提出了一种用于连续纵向数据的选择模型,该模型受非随机丢失的影响。它激起了有关此类模型作用的争论。最初的热情之后,人们对这种模型始终基于的强有力但无法检验的假设表示怀疑。从那时起,就出现了这样的观点:理想情况下,应将这些模型作为敏感性分析的一部分。本文提出了一种基于本地影响力的敏感性评估的正式而灵活的方法(Cook,1986,《皇家统计学会杂志》,系列B 48,133-169)。探索了在非随机辍学方向上干扰随机缺失辍学模型的影响。该方法应用于来自大鼠的睾丸激素抑制作用的随机实验数据。 [参考:21]

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