Performance Enhancing Synergy Between a Wheat Hydrolysate and Recombinant Human Serum Albumin in SP2/0 Hybridoma Cells

摘要

In an effort to mitigate potential risks associated with the introduction of adventitious agents from animal-derived media components, the biopharmaceutical industry has largely shifted to serum-free and/or chemically defined media in cell culture production systems. Successful serum-free media formulations have been developed using plant-derived protein hydrolysates in combination with recombinant supplements such as insulin, transferrin, and human serum albumin, produced in nonanimal systems.