The Influence of Biophysics to the Physiology of the Cells and Tissues

摘要

Along with the advancement of analytic tools at nano scale precision, scientists gain access to the biophysical properties of the cells. Interpretation of physiology and pathology from interplay between cell, tissue and the physical mechanical alterations of its microenvironment become feasible. The nanotribology opened a new era in biomedicine from the bottom and now we know that cell-cell interaction and cell-extracellular matrix adhesion as well as the physical forces induce a complex biochemical process and gene expression regulation and ultimately contribute to the phenotype observed. This paper aimed to provide a comprehensive review of the nano/micro technologies developed for the measurement of biophysical properties of cells and the biophysical bases of the cell.