The relationship between inflammatory markers and coronary collateral circulation should be evaluated together with cardiovascular medications in stable coronary artery disease

摘要

We were grateful to read an interesting article by Uysal et al,' evaluating the association of neutrophil to lymphocyte ratio (NLR) with coronary collateral circulation (CCC) in a total of 521 consecutive patients with stable coronary artery disease (CAD). They have found that increased NLR (odds ratio [OR]: 0.70, 95% confidence interval [CI]: 0.62-0.80; P < .01) and fasting plasma glucose (OR: 0.995, 95% CI: 0.991-0.999) levels were independent predictors of CCC in multivariate regression analysis. Additionally, NLR level of >2.75 to predict poor CCC has 65% sensitivity and 68% specificity (area under the curve: 0.714, 95% CI: 0.66-0.75).