Phakic anterior chamber lenses in very high myopia: An 18-month follow up

摘要

Background: To evaluate the efficacy and tolerance of two different foldable anterior chamber phakic intraocular lenses for high myopia. Design: A prospective interventional case series at the Eye Clinic, Kartal Training and Research Hospital, Istanbul, Turkey. Participants: Sixty-two eyes of 31 patients received iris-claw lens (group 1) (Artiflex AC 401, Ophtec), and 43 eyes of 22 patients received angle-supported lens (group 2) (I-Care, Corneal). Methods: The mean preoperative spherical equivalents for group 1 and group 2 were -12.13D and -18.95D, respectively. Endothelial cell density was measured at day 1 and at 1, 3, 6, 12 and 18months for follow ups. Main Outcome Measures: Percentage change in endothelial cell density and improvement in visual acuity. Results: At the 18-months follow up, uncorrected visual acuity improved to logMAR 0.37±0.23 from 1.60±0.10 in group 1, and logMAR 0.47±0.14 from 0.70±0.20 in group 2; best spectacle corrected visual acuity improved to logMAR 0.23±0.22 from logMAR 0.36±0.14) in group 1, and logMAR 0.29±0.18 from logMAR 0.50±0.20) in group 2 (P0.001, in both groups). Mean decreased endothelial cell density was 241 cells/mm 2 (8.61%) and 223 cells/mm 2 (8.42%) at 18months follow up in group 1 and 2, respectively (P=0.17) but significant in comparison to preoperative values for both groups (P0.001). Conclusions: Although both iris-claw and angle-supported lenses offer good refractive outcomes significant endothelial cell density was observed at 18months follow up.