Difficulties and mistakes in the diagnosis of atypical endometrial hyperplasia

摘要

687 endometrial biopsy specimens with morphological diagnosis "atypical endometrial hyperplasia" were examined by pathologists from the city cancer. The specimens were obtained from 32 hospitals of Saint Petersburg. They revealed atypical endometrial hyperplasia in 47 (6.8%) cases, endometrial adenocarcinoma in 54 (7.9%), typical hyperplasia in 211 (30.7%), polyp in 165 (24%), proliferative endometrium in 89 (13.0%), secretory endometrium in 80 (11.7%), and atrophic endometrium in 10 (1.4%). Thirty-one (4.5%) biopsy specimens failed to provide evidence. Also biopsy and surgery specimens (n = 78) were compared. Hysterectomy was performed in atypical endometrial hyperplasia. Comparison of the diagnoses revealed atypical endometrial hyperplasia in 14 (17.9%) cases, endometrial adenocarcinoma in 41 (52.7%), typical endometrial hyperplasia in 21 (26.9%), and polyp in 2 (2.5%).