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Clinical application of multifocal visual evoked potentials in children with epilepsy caused by intracranial disease

机译:多灶性视觉诱发电位在颅内疾病引起的癫痫患儿中的临床应用

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PURPOSE: We investigated whether visual field defects could be objectively evaluated using multifocal visual evoked potential(m-VEP) in two children with epilepsy caused by intracranial disease in whom it was difficult to measure the visual field. METHODS: To determine normal waves in m-VEP, recording was performed using a visual evoked response imaging system(VERIS)Junior Science program (Mayo, Aichi, Japan) in 20 healthy children (20 eyes); peak latency and amplitude were used for assessment. In the two children with epilepsy, m-VEPs were recorded, and compared with the results of static perimetry or the lesions observed by Magnetic Resonance Imaging (MRI). RESULTS: In the 20 healthy children, there was no significant difference in the peak latency or amplitude among 4 quadrants by one-way analysis of variance. m-VEP in the children with epilepsy showed abnormal waves, corresponding to the visual field defects in the static perimetry or the lesions observed by MRI. CONCLUSIONS: Objective evaluation of visual field defects using m-VEP may be useful in children with epilepsy caused by intracranial disease in whom kinetic/static perimetry as a subjective examination is difficult.
机译:目的:我们调查了在两个难以测量视野的颅内疾病引起的癫痫患儿中,是否可以使用多焦点视觉诱发电位(m-VEP)客观评估视野缺损。方法:为了确定m-VEP中的正常波,使用视觉诱发反应成像系统(VERIS)初级科学程序(日本爱知县梅野市)对20名健康儿童(20只眼睛)进行了记录;峰值潜伏期和振幅用于评估。在两个癫痫患儿中,记录m-VEP,并将其与静态视野检查或磁共振成像(MRI)观察到的病变进行比较。结果:在20名健康儿童中,通过单向方差分析,在4个象限中,峰值潜伏期或振幅没有显着差异。在癫痫患儿中,m-VEP显示异常波,对应于静态视野检查中的视野缺损或MRI观察到的病变。结论:使用m-VEP客观评估视野缺损对于颅内疾病引起的癫痫患儿可能是有用的,这些患者的动/静视力检查很难进行主观检查。

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