Novel alpha-fluorinated cyclic phosphite and phosphinite ligands and their Rh-complexes as suitable catalysts in hydroformylation

摘要

Asymmetrical cyclic phosphite and phosphinite ligands of a novel type bearing either trifluoromethyl or pentafluorophenyl group were synthesized using > PCl or > PN < species and racernic fluorinated alcohols. The P-ligands were converted to complexes of Rh-111(L)(Cp*)Cl-2 type (where L = phosphite or phosphinite) and, in two instances, their stereostructures were evaluated by X-ray analysis. These complexes along with in situ systems, formed from Rh(CO)(2)(acac) precursor and the corresponding ligand, were tested in the hydroformylation of styrene. Both systems provided excellent hydroformylation activities at 100 degrees C. Using the Rh-1 in situ systems, moderate and high regioselectivities towards the branched aldehyde (2-phenyl-propanal) were obtained at 100 and 40 degrees C, respectively. (c) 2005 Elsevier B.V. All rights reserved.