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外文期刊>Diabetes/metabolism research and reviews
>Editors' note to Raz and Eldor's commentary 'Rational therapy for diabetes: Early recognition of adverse effects and avoidance of disruptive false alarms'. Diabetes Metab Res Rev 2012
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Editors' note to Raz and Eldor's commentary 'Rational therapy for diabetes: Early recognition of adverse effects and avoidance of disruptive false alarms'. Diabetes Metab Res Rev 2012
In order to target and image MMP-2 activity using optical imaging, we developed a panel of new MMP-2 probes based on Cy5 and QSY21 as fluorophore/quencher FRET partners, separated by various MMP-2 specific peptide substrates. We compared these probes for their specificity against other MMPs, their rate of activation by MMP-2 and their initial quenching.
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