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Comment on 'Antibiotics to reduce post-tonsillectomy morbidity'

机译:评论“抗生素可减少扁桃体切除术后的发病率”

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Last year's Food and Drug Administration (FDA) safety communication regarding reported codeine-related deaths in children undergoing adenotonsillar surgery has brought the subject of morbidity after tonsillectomy to the forefront of many of our thoughts. We reproduce [pg 154] the, recently updated, Cochrane review, published in December 2012, examining the efficacy of antibiotics in reducing post-tonsillectomy morbidity. This review encompasses 10 trials including a total of 1035 patients. The authors conclude that there is no rationale in giving antibiotics routinely to patients undergoing tonsillectomy. The post-operative complications that cause most concern for doctors and patients are pain and secondary haemorrhage, and it has traditionally been postulated by ENT surgeons that these are caused by infection of the tonsillar bed. There is, however, very little evidence to support this view. So where do we stand with symptom control after tonsillectomy? There is good evidence to support the use of a dose of perioperative steroid such as dexamethasone. The recently published meta-analysis suggesting an increase in return to theatre following their use was skewed by a single study using very high dosage. In general, the evidence supports a single dose of dexamethasone, and this recommendation is supported by the Scottish Intercollegiate Guideline Network and American Academy of Otolaryngology Clinical Practice Guideline.
机译:去年,美国食品药品监督管理局(FDA)关于进行腺扁桃体手术的儿童中可待因相关死亡的报道引起了安全通报,这使得扁桃体切除术后的发病率成为我们许多思想的重中之重。我们复制[pg 154],最近更新,于2012年12月发表的Cochrane综述,研究了抗生素在降低扁桃体切除术后的发病率中的功效。该评价包括10项试验,包括1035名患者。作者得出的结论是,对扁桃体切除术患者常规给予抗生素是没有道理的。令医生和患者最关注的术后并发症是疼痛和继发性出血,耳鼻喉科医师传统上认为,这些是由扁桃体床感染引起的。但是,很少有证据支持这种观点。那么扁桃体切除术后我们在控制症状方面应该站在哪里呢?有充分的证据支持一定剂量的围手术期类固醇如地塞米松的使用。最近发表的荟萃分析表明,一项使用很高剂量的研究使使用剧本后返回剧院的收益增加。通常,证据支持地塞米松单剂量,并且该建议得到苏格兰大学间指南网络和美国耳鼻咽喉科学院临床实践指南的支持。

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