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首页> 外文期刊>JPEN. Journal of parenteral and enteral nutrition. >Hospital readmissions for catheter-related bloodstream infection and use of ethanol lock therapy: Comparison of patients receiving parenteral nutrition or intravenous fluids in the home vs a skilled nursing facility
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Hospital readmissions for catheter-related bloodstream infection and use of ethanol lock therapy: Comparison of patients receiving parenteral nutrition or intravenous fluids in the home vs a skilled nursing facility

机译:因导管相关的血流感染而住院再入院和使用乙醇锁定疗法:在家与熟练护理机构中接受肠胃外营养或静脉输液的患者的比较

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摘要

Background: Catheter-related bloodstream infection (CRBSI) is the most serious long-term infectious complication of long-term home parenteral nutrition (PN). Ethanol is being used more commonly as a catheter locking solution in the home PN setting for prevention of CRBSI; however, no current literature reports the use of ethanol lock (ETL) in skilled nursing facility (SNF) patients. Methods: The authors evaluated the number of hospital readmissions for CRBSI and length of stay between SNF (not receiving ETL) and home patients (receiving or not receiving ETL) receiving PN or intravenous fluid therapy. Results: SNF patients had a significantly longer length of stay (LOS) for CRBSI hospital admissions compared with patients receiving PN at home with or without ETL (P <.001; 16 vs 8 vs 8 days). There was no LOS difference for CRBSI between home patients with or without ETL. Home PN patients not receiving ETL were more likely to have a CRBSI from Staphylococcus sp (48% vs 27%; P =.015), whereas SNF PN patients not receiving ETL were more likely to have a CRBSI from Enterococcus sp (16% vs 3%; P =.004). Conclusion: Despite different causative organisms and medical acuity likely affecting the differences observed in LOS, the SNF population is another setting ETL can be used to prevent CRBSI.
机译:背景:导管相关的血流感染(CRBSI)是长期家庭肠外营养(PN)的最严重的长期感染并发症。在家庭PN环境中,乙醇通常被用作导管锁定解决方案,以预防CRBSI。但是,目前没有文献报道在熟练护理机构(SNF)患者中使用乙醇锁(ETL)。方法:作者评估了CRBSI的住院再入院次数以及SNF(不接受ETL)和接受PN或静脉输液治疗的家庭患者(接受或不接受ETL)之间的住院时间。结果:与在家中接受或未接受ETL PN的患者相比,SNF患者接受CRBSI住院的住院时间(LOS)明显更长(P <.001; 16天,8天和8天)。有或没有ETL的家庭患者之间CRBSI的LOS没有差异。未接受ETL的家庭PN患者更有可能获得葡萄球菌的CRBSI(48%vs 27%; P = .015),而未接受ETL的SNF PN患者更可能具有肠球菌的CRBSI(16%vs 3%; P = .004)。结论:尽管不同的病原体和医疗敏锐度可能会影响LOS观察到的差异,但SNF人群是另一个可以用来预防CRBSI的环境。

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