首页> 外文期刊>Journal of gastrointestinal surgery: official journal of the Society for Surgery of the Alimentary Tract >Serum CA19-9 is a significant predictor among preoperative parameters for early recurrence after resection of pancreatic adenocarcinoma.
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Serum CA19-9 is a significant predictor among preoperative parameters for early recurrence after resection of pancreatic adenocarcinoma.

机译:血清CA19-9是胰腺癌切除术后早期复发的术前指标中的重要预测指标。

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摘要

To evaluate the preoperative factors predictive of postoperative early recurrence in patients with resected pancreatic cancer focusing on the serum CA19-9 value.One hundred fifty-four patients undergoing surgical resection for pancreatic cancer were enrolled in this study. Univariate and multivariate analyses were performed to determine the predictors of early recurrence which was defined as relapse within 6?months after surgery.On ROC curve analysis, the cutoff value of CA19-9 was determined to be 100?U/ml. Of 73 patients with CA19-9 value?≥?100?U/ml, 39 (53?%) had early recurrence. In contrast, only 9 of 81 patients (11?%) with CA19-9 value?
机译:以血清CA19-9值为基础,评价切除胰腺癌患者术后早期复发的术前因素。本研究共纳入154例接受胰腺癌手术切除的患者。进行单因素和多因素分析以确定早期复发的预测指标,定义为手术后6个月内复发。ROC曲线分析确定CA19-9的临界值为100μU/ ml。在CA19-9值≥100 U / ml的73例患者中,有39例(53%)早期复发。相反,在CA19-9值≤<100?U / ml的81位患者中,只有9位(11%)在早期复发(p <0.001)。多因素分析显示,CA19-9值≥100?U / ml(比值比为11.2)是早期复发的重要预测指标。 CA19-9值 100U / ml和21.2%,9.4%的患者的3年和5年总生存率和中位生存时间分别为47.3%,40.1%和31月。且CA19-9值≥100?U / ml的患者在16个月内(p 0.001)。术前C​​A19-9值≥100 U / ml是早期复发和复发的重要预测指标。胰腺腺癌切除后预后不良。

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