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Poor long-term clinical results of saddle prosthesis after resection of periacetabular tumors tumor

机译:髋臼周围肿瘤切除术后鞍式假体长期临床效果差

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Background: The saddle prosthesis originally was developed to reconstruct large acetabular defects in revision hip arthroplasty and was used primarily for hip reconstruction after periacetabular tumor resections. The long-term survival of these reconstructions is unclear. Questions/purpose: We therefore examined the long-term function, complications, and survival in patients treated with saddle prostheses after periacetabular tumor resection. Patients and Methods: Between 1987 and 2003 we treated 17 patients with a saddle prosthesis after periacetabular tumor resection (12 chondrosarcomas, three osteosarcomas, one malignant fibrous histiocytoma, one metastasis). During followup, 11 patients died, resulting in a median overall survival of 49 months (95% CI, 30-68 months). The remaining six patients were alive without disease (mean followup, 12.1 years; range, 8.3-16.8 years). In one patient the saddle prosthesis was removed after 3 months owing to dislocation and infection. We obtained SF-36 questionnaires, Toronto Extremity Salvage Scores (TESS), and Musculoskeletal Tumor Society (MSTS) scores. Results: Thirteen of 17 patients used walking assists for mobilization at last followup: eight patients required two crutches, five needed one crutch, and one did not use any walking aids. The other three patients were not able to mobilize independently and only made bed to chair transfers. The mean hip flexion in the six surviving patients was 60 (range, 40 -100) at last followup. Local complications were seen in 14 of the 17 patients: nine wound infections, seven dislocations, and two leg-length discrepancies requiring additional surgery. In the five surviving patients with their index prosthesis still in situ, the mean MSTS score at long-term followup was 47% (range, 20%-77%), the mean TESS score was 53% (range, 41%-67%), and the mean composite SF-36 physical and mental component summaries were 43.9 and 50.6, respectively. Conclusion: Reconstruction with saddle prostheses after periacetabular tumor surgery has a high risk of complications and poor long-term function with limited hip flexion; therefore, we no longer use the saddle prosthesis for reconstruction after periacetabular tumor resections. Level of Evidence: Level IV, retrospective case series. See the Guideline for Authors for a complete description of levels of evidence.
机译:背景:鞍形假体最初是为重建髋关节置换术中的大型髋臼缺损而开发的,主要用于髋臼周围肿瘤切除术后的髋关节重建。这些重建的长期生存尚不清楚。问题/目的:因此,我们检查了髋臼周围肿瘤切除术后接受鞍状假体治疗的患者的长期功能,并发症和存活率。患者和方法:在1987年至2003年之间,我们对17例髋臼假体切除术后的鞍状假体进行了治疗(12例软骨肉瘤,3例骨肉瘤,1例恶性纤维组织细胞瘤,1例转移)。在随访期间,有11名患者死亡,导致平均总生存期为49个月(95%CI,30-68个月)。其余6例患者没有疾病存活(平均随访时间:12.1年;范围:8.3-16.8年)。在一名患者中,由于脱位和感染,在3个月后取下了鞍状假体。我们获得了SF-36问卷,多伦多肢体救助评分(TESS)和肌肉骨骼肿瘤学会(MSTS)评分。结果:17名患者中有13名在最后一次随访中使用了助行器:8名患者需要两个拐杖,五名需要一根拐杖,而一名则没有使用任何助行器。其他三名患者无法独立动员,只能从床到椅子转移。在最后一次随访中,六名幸存患者的平均髋屈曲为60(范围40 -100)。 17例患者中有14例发生了局部并发症:9例伤口感染,7例脱位和2例腿长不符,需要进一步手术。在5例仍保留原位假体的存活患者中,长期随访的平均MSTS评分为47%(范围20%-77%),平均TESS评分为53%(范围41%-67%) ),SF-36身体和精神成分的综合平均数分别为43.9和50.6。结论:髋臼周围肿瘤手术后用鞍状假体重建具有较高的并发症风险,长期功能较差,髋关节屈曲受限。因此,我们不再使用鞍状假体进行髋臼周围肿瘤切除术后的重建。证据级别:第四级,回顾性病例系列。有关证据水平的完整说明,请参见《作者指南》。

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