Kinetic study of solvent effects on the hydrolysis of di-2-chloroaniline phosphate in dioxane and dimethyl sulfoxide-water medium

摘要

Kinetic study of di-2-chloroaniline phosphate was carried out in dioxane and dimethyl sulfoxide-water mixtures of varying compositions 20-50% (v/v). The rate of reaction increases with increasing proportion of dioxane and dimethyl sulfoxide at 80 and 90 °C. The activation parameters (E_a, ΔH~≠, ΔG~≠, -ΔS~≠) have been evaluated and variations of these parameters have been explained on thse basis of solvent-solute interaction, solvent of the transition state of the medium.