Effects of tissue plasminogen activator timing on blood-brain barrier permeability and hemorrhagic transformation in rats with transient ischemic stroke

Zhang Yanrong; Wang Yi; Zuo Zhiyi; Wang Zhongxing; Roy Jack; Hou Qinghua; Tong Elizabeth; Hoffmann Angelika; Sperberg Emily; Bredno Joerg; Berr Stuart S.; Xie Mingxing; Lee Kevin; Winterrnark Max

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Effects of tissue plasminogen activator timing on blood-brain barrier permeability and hemorrhagic transformation in rats with transient ischemic stroke

机译：组织纤溶酶原激活物时机对短暂性脑卒中大鼠血脑屏障通透性和出血转化的影响

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The goal of our study was to determine if the timing of the tissue plasminogen activator (tPA) administration influenced its effect on blood brain barrier (BBB) permeability and the subsequent risk of hemorrhagic transformation.

机译：我们研究的目的是确定组织纤溶酶原激活物（tPA）的给药时间是否影响其对血脑屏障（BBB）通透性的影响以及随后发生出血性转化的风险。

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《Journal of the Neurological Sciences: Official Bulletin of the World Federation of Neurology》 |2014年第2期|共7页
作者
Zhang Yanrong; Wang Yi; Zuo Zhiyi; Wang Zhongxing; Roy Jack; Hou Qinghua; Tong Elizabeth; Hoffmann Angelika; Sperberg Emily; Bredno Joerg; Berr Stuart S.; Xie Mingxing; Lee Kevin; Winterrnark Max;
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正文语种 eng
中图分类神经病学;
关键词
Blood-brain barrier permeability; Hemorrhagic transformation; Ischemic stroke; Tissue plasminogen activator; MR imaging;

机译：血脑屏障通透性;出血性转化;缺血性中风;组织纤溶酶原激活物;MR成像;

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1. Effects of tissue plasminogen activator timing on blood-brain barrier permeability and hemorrhagic transformation in rats with transient ischemic stroke [J] . Zhang Yanrong, Wang Yi, Zuo Zhiyi, Journal of the Neurological Sciences: Official Bulletin of the World Federation of Neurology . 2014,第1a2期

机译：组织纤溶酶原激活物时机对短暂性脑卒中大鼠血脑屏障通透性和出血转化的影响
2. Recombinant tissue plasminogen activator increases blood-brain barrier disruption in acute ischemic stroke: an MR imaging permeability study. [J] . Kassner A, Roberts TP, Moran AJNR. American journal of neuroradiology . 2009,第10期

机译：重组组织纤溶酶原激活物增加急性缺血性卒中的血脑屏障破坏：一项MR成像通透性研究。
3. Recombinant Tissue Plasminogen Activator Increases Blood-Brain Barrier Disruption in Acute Ischemic Stroke: An MR Imaging Permeability Study [J] . A. Kassner, T.P.L. Roberts, B. Moran, American Journal of Neuroradiology . 2009,第10期

机译：重组组织纤溶酶原激活剂增加急性缺血性卒中的血脑屏障破坏：MR成像通透性研究。
4. Investigations into intraocular Injection of Recombinant Tissue Plasminogen Activator (rTPA) for the Treatment of Trauma-induced Intraocular Hemorrhages in Birds [C] . Ruediger T. Korbel, Med Vet Habil, Cert Spec Vet Ophthalmol Annual Conference of the Association of Avian Veterinarians . 2003

机译：对重组组织纤溶酶原激活剂（RTPA）的对鸟类诱导的鸟类诱导的眼内出血进行调查
5. Magnetic resonance imaging investigations of ischemic stroke, intracerebral hemorrhage and blood-brain barrier pathology. [D] . Karki, Kishor. 2009

机译：缺血性脑卒中，脑出血和血脑屏障病理的磁共振成像研究。
6. Recombinant Tissue Plasminogen Activator Increases Blood-Brain Barrier Disruption in Acute Ischemic Stroke: An MR Imaging Permeability Study [O] . A. Kassner, T.P.L. Roberts, B. Moran, 2009

机译：重组组织纤溶酶原激活剂增加急性缺血性中风中的血脑屏障中断：MR成像渗透性研究
7. Recombinant Tissue Plasminogen Activator Increases Blood-Brain Barrier Disruption in Acute Ischemic Stroke: An MR Imaging Permeability Study [O] . A. Kassner, T. P. L. Roberts, B. Moran, 2015

机译：重组组织型纤溶酶原激活剂增加急性缺血性卒中的血脑屏障破坏：mR成像渗透性研究

Effects of tissue plasminogen activator timing on blood-brain barrier permeability and hemorrhagic transformation in rats with transient ischemic stroke

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