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Validity of a simple Internet-based outcome-prediction tool in patients with total hip replacement: A pilot study

机译:一个简单的基于互联网的结果预测工具在全髋关节置换患者中的有效性:一项前瞻性研究

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We developed a user-friendly Internet-based tool for patients undergoing total hip replacement (THR) due to osteoarthritis to predict their pain and function after surgery. In the first step, the key questions were identified by statistical modelling in a data set of 375 patients undergoing THR. Based on multiple regression, we identified the two most predictive WOMAC questions for pain and the three most predictive WOMAC questions for functional outcome, while controlling for comorbidity, body mass index, age, gender and specific comorbidities relevant to the outcome. In the second step, a pilot study was performed to validate the resulting tool against the full WOMAC questionnaire among 108 patients undergoing THR. The mean difference between observed (WOMAC) and model-predicted value was -1.1 points (95% confidence interval, CI -3.8, 1.5) for pain and -2.5 points (95% CI -5.3, 0.3) for function. The model-predicted value was within 20% of the observed value in 48% of cases for pain and in 57% of cases for function. The tool demonstrated moderate validity, but performed weakly for patients with extreme levels of pain and extreme functional limitations at 3 months post surgery. This may have been partly due to early complications after surgery. However, the outcome-prediction tool may be useful in helping patients to become better informed about the realistic outcome of their THR.
机译:我们为因骨关节炎而进行全髋关节置换(THR)的患者开发了一种用户友好的基于Internet的工具,以预测术后的疼痛和功能。第一步,通过统计建模,在375名接受THR的患者的数据集中确定了关键问题。基于多元回归,我们在控制合并症,体重指数,年龄,性别和与合并症相关的特定合并症的同时,确定了两个最能预测疼痛的WOMAC问题和三个最能预测功能性WOMAC问题。第二步,进行了一项初步研究,以针对108名接受THR的患者,针对完整的WOMAC调查表验证所得工具。疼痛的观察值(WOMAC)与模型预测值之间的平均差为-1.1点(95%置信区间,CI -3.8,1.5),功能为-2.5点(95%CI -5.3,0.3)。在48%的疼痛病例和57%的功能病例中,模型预测值在观察值的20%以内。该工具显示出中等有效性,但在术后3个月对极端疼痛和极端功能受限的患者效果较差。这可能部分是由于手术后的早期并发症。但是,结果预测工具可能有助于帮助患者更好地了解THR的实际结果。

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