The regioselective methylation of polycyclic aromatic hydrocarbons through tricarbonylchromium coordination

摘要

Deprotonation, methylation, and air oxidation of polycyclic arenes coordinated to chromium(0), (eta(6)-arene)Cr(CO)(3), produced ring-methylated products with high selectivity and in good yield. This procedure gave 3-methylbenz[a]anthracene from (eta(6)-benz[a]anthracene)Cr(CO)(3), 3-methylphenanthrene from (eta(6)-phenanthrene)Cr(CO)(3), 2-acetyl-6-methylphenanthrene from (eta(6)-2-acetylphenanthrene)Cr(CO)(3), and 3,7, 12-trimethylbenz[a]anthracene from (eta(6)-7,12-dimethylbenz[a]anthracene)Cr(CO)(3). [References: 21]