The eponym Wilbrand's knee refers to a bundle of nerve fibers that make a characteristic loop along their. pathway in the central nervous system. If involved in a pathological process, the "knee" can give rise to a typical disorder the details of which will be given in the Neurognostics Answer.Hermann Wilbrand (1851-1935) who put forward this idea was born in Giessen, a small university town in the center of Germany, where his father Julius Wilbrand (1811-1894) was professor of "Staatsarzneikunde," a topic mainly dealing with forensic medicine. The grandfather (Johann Bernhard Wilbrand, 1779-1846) had been a professor of anatomy, physiology, and natural history. As an exponent of Naturphilosophie, a German form of the philosophy of nature chiefly identified with the philosopher Friedrich Schelling (1775-1854), he had taught the idea of life as a metaphysical concept not accessible to experimental studies as practiced in modern life sciences. Bernhard Wilbrand's influence vanished after the chemist Justus Liebig (1803-1873) had come to Giessen and opened the modern scientific era there.
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