Synthesis, Characterization and Antimicrobial Activities of Transition Metal Complexes of methyl 2-{[(E)-(2-hydroxyphenyl)methylidene]amino}benzoate

摘要

New metal complexes with Schiff base ligand methyl 2-{[(E)-(2-hydroxyphenyl)methylidene]amino}benzoate, were synthesized and characterized. Elemental analyses, EI-MS, H-1 and C-13{H-1}-NMR were used for ligand characterization whereas elemental analyses, EI-MS, IR and UV-Visible spectroscopic techniques were used for the transition metal compounds. All these analyses reveal the bis arrangement of the ligand around the metal centres. The compounds were studied for their antimicrobial activities against different pathogenic microbial species. It was found that the Schiff base ligand was completely inactive in comparison to the transition metal compounds. It was also observed that nickel based metal complex shown good results against Candida albican (25 mm) and zinc based metal complex against Agrobacterium tumefaciens (16 mm).