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SIMPLIFYING DETECTION OF MILD COGNITIVE IMPAIRMENT SUBTYPES

机译:轻度认知障碍亚型的检测

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To the Editor: Older adults with mild cognitive impairment (MCI) are a heterogeneous group. Identification of MCI is clinically based, and diagnosis is not restricted to individuals only with memory problems, because impairments in other cognitive domains, in isolation or in conjunction with memory impairment, are recognized. This heterogeneity has led to an algorithm to categorize individuals with MCI into four subtypes: a major subdivision on amnestic and nonamnestic status followed by further subclassification into single- and multiple-domain categories. Subcategori-zation of MCI has important implications for research, prognosis, and potential early treatment, although MCI subcategorization is difficult to implement based only on clinical judgment, and a complete neuropsychological assessment is not always available. Therefore, a need exists for a simple methodology based on tests commonly used in clinical practice. Since its description, the Montreal Cognitive Assessment (MoCA) test has become a valuable tool in the detection of people with MCI. It was designed to address some of the limitations of the Mini-Mental State Examination (MMSE) because it assesses a broader range of cognitive domains and with more detail. Differences across MoCA cognitive domains have been reported in people with Parkinson's disease with and without cognitive impairment. This has not been explored in people with MCI. It was postulated that the MoCA may provide sufficient information in scoring different cognitive domains to assist in MCI subcategorization.
机译:致编辑:患有轻度认知障碍(MCI)的老年人属于异类。 MCI的鉴定是基于临床的,并且诊断不仅限于患有记忆问题的个体,因为可以识别其他认知领域的损害,这些损害是孤立的或与记忆损害相结合的。这种异质性导致了一种算法,可将具有MCI的个人分为四个亚类型:记忆删除和非记忆状态的主要细分,然后进一步细分为单域和多域类别。 MCI的亚分类对研究,预后和潜在的早期治疗具有重要意义,尽管仅基于临床判断很难实施MCI的亚分类,而且并不总是可以进行完整的神经心理学评估。因此,需要一种基于临床实践中常用的测试的简单方法。自描述以来,蒙特利尔认知评估(MoCA)测试已成为检测MCI患者的宝贵工具。它旨在解决迷你精神状态考试(MMSE)的某些局限性,因为它可以评估更广泛的认知领域,并且具有更多的细节。据报道,患有和不患有认知障碍的帕金森氏病患者在MoCA认知域之间存在差异。 MCI患者尚未对此进行探索。据推测,MoCA可能会提供足够的信息来评分不同的认知领域,以帮助MCI进行亚分类。

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