Secular trends of body mass index in North Indian children with Type 1 diabetes do not support the Accelerator Hypothesis

摘要

ObjectiveThe accelerator hypothesis, which proposes a link between Type 1 diabetes (T1D) and Type 2 diabetes (T2D) through weight-related insulin resistance, remains untested in developing countries with increasing rates of childhood obesity and T1D, and different ethnicities. We aimed to test the accelerator hypothesis in the context of a significant increase in T1D at our centre.