Reply: Aspiration thrombectomy: An easily forgiven 'latecomer'

摘要

We are thankful to De Rosa and colleagues for their additional analysis of, and insight into the topic covered in our report (1). Although we were unable to directly replicate their findings, their findings are interesting and hypothesis generating. It is conceivable that aspiration thrombectomy will have a U-shaped relationship with ischemic time when more trials are included. With longer ischemic times, the thrombus becomes more organized and is subsequently harder to retrieve with manual aspiration catheters. This hypothesis should be actively investigated in future studies on this topic.