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首页> 外文期刊>Journal of Process Control >Disturbance rejection for the control of batch end-product quality using latent variable models
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Disturbance rejection for the control of batch end-product quality using latent variable models

机译:使用潜在变量模型抑制干扰来控制批次最终产品的质量

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The control of batch end-product quality is an important issue in many high value-added manufacturing industries, particularly specialty chemicals and pharmaceuticals. An attractive approach for controlling such systems is to apply partial least squares (PLS) models, which can utilize the low-dimensional latent variable (or score) space with the corresponding control optimization performed on these few latent variables. The manipulated variable trajectories (MVTs) can then be reconstructed from the optimized scores. The existing PLS-based batch end-product quality control methodology does not incorporate the disturbance model in its formulation. As a result, it is demonstrated in this paper that these control formulations can be incapable of adequate disturbance rejection. To reject disturbances adequately, it is necessary to utilize feedback information and re-compute optimal control sequences at multiple instants during a batch run. However, this can lead to erratic control action, resulting in the deterioration of batch end-product quality. To resolve this issue, a revised PLS-based batch end-product quality controller is proposed in this paper that explicitly accounts for disturbance induced plant-model mismatch by including a simple disturbance model. Furthermore, the proposed controller formulation adds hard constraints to incremental changes of the re-computed control sequences to avoid erratic behavior in the case of multiple control decision points. The ability of the proposed control scheme to reject disturbances and obtain desirable MVTs is demonstrated using a benchmark simulation of a fed-batch fermentation process.
机译:在许多高附加值的制造业中,尤其是特种化学品和药品,批次最终产品质量的控制是一个重要的问题。控制此类系统的一种有吸引力的方法是应用局部最小二乘(PLS)模型,该模型可以利用低维潜在变量(或得分)空间,并对这几个潜在变量执行相应的控制优化。然后可以从优化得分中重建操纵变量轨迹(MVT)。现有的基于PLS的批次最终产品质量控制方法没有在其配方中包含干扰模型。结果,在本文中证明了这些控制配方可能无法充分抑制干扰。为了充分消除干扰,有必要在批处理运行的多个时刻利用反馈信息并重新计算最佳控制序列。但是,这可能导致控制动作不稳定,导致批次最终产品质量下降。为了解决这个问题,本文提出了一种基于PLS的改进的批次最终产品质量控制器,该控制器通过包括一个简单的干扰模型来明确解决由干扰引起的工厂模型不匹配的问题。此外,提出的控制器公式对重新计算的控制序列的增量变化增加了硬约束,以避免在多个控制决策点的情况下出现不稳定行为。使用补料分批发酵过程的基准仿真,证明了所提出的控制方案抑制干扰并获得理想的MVT的能力。

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