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Trajectories of Anxiety Among Women with Breast Cancer: A Proxy for Adjustment from Acute to Transitional Survivorship

机译:乳腺癌妇女的焦虑轨迹:从急性生存到过渡生存的调整代理

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Anxiety is one of the main components of distress among women with breast cancer (BC), particularly in the early stages of the disease. Changes in anxiety over time may reflect the process of adjustment or lack thereof. The process of adjustment in the traverse of acute to transitional stages of survivorship warrants further examination. To examine the trajectory of anxiety and the specific patterns that may indicate a lack of adjustment within 2years following BC surgery, survey data from a 2-year prospective cohort study of 725 women with BC were analyzed by Mixture Growth Modelling and logistic regression and Analysis of Variance. A piece-wise growth curve displayed the best fit to the data, indicating a significant decrease in anxiety in the first year, followed by a slower rate of change during the second year. Four classes of trajectories were identified: High Stable, High Decrease, Mild Decrease, and Low Decrease. Of these, High Stable anxiety showed the most substantive indications of lack of adjustment. This subgroup was predominantly characterized by sociodemographic variables such as financial difficulties. Our results support an emphasis on the transitional nature of the stage that follows the end of primary active treatment and imply a need for supportive follow up care for those who display lack of adjustment at this stage.
机译:焦虑是乳腺癌女性的困扰的主要因素之一,尤其是在该疾病的早期阶段。焦虑随着时间的变化可能反映出其适应过程或缺乏适应过程。从生存的急性期到过渡期的调整过程值得进一步研究。为了检查焦虑的轨迹和可能表明在BC手术后2年内缺乏调整的特定模式,通过混合增长模型和logistic回归分析了来自725名BC妇女的为期2年的前瞻性队列研究的调查数据。方差。分段增长曲线显示出与数据的最佳拟合,表明第一年的焦虑显着降低,第二年的变化率降低。确定了四类轨迹:高稳定性,高减小,轻度减小和低减小。其中,高度稳定的焦虑表现出缺乏调整的最实质性迹象。该亚组的主要特征是社会人口统计学变量,例如经济困难。我们的结果支持重点在于初次积极治疗结束后该阶段的过渡性质,并暗示需要为在此阶段表现出缺乏适应能力的患者提供支持性后续护理。

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