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Jejunal pedicle grafts for reconstruction of the esophagus in children.

机译:空肠椎弓根移植物重建儿童食道。

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摘要

OBJECTIVE: Reconstruction of the esophagus in children remains a challenge. Although jejunal grafts retain peristaltic activity, large series with long-term follow up are rare. We like to present our experience in a series of 24 children. METHODS: In the period 1988 through 2005, 24 children received an orthotopic jejunal pedicle graft reconstruction of the esophagus. Nineteen had esophageal atresia (18 had no distal fistula; all but 1 had a jejunal graft as a primary procedure), 3 had an extensive caustic stricture, and 2 had a peptic stricture. All strictures had been dilated many times, and peptic strictures had been treated with antireflux surgery as well. Median age at reconstruction was 76 days in the esophageal atresia group. The technique involves a right-sided thoracotomy with preparation of the esophageal ends or resection of the diseased esophagus. At laparotomy, a small pediculated jejunal graft is prepared and placed transhiatally in an orthotopic position in the right chest. RESULTS: All patients survived, and none of the grafts were lost. There were 5 intrathoracic leaks, 4 in the esophageal atresia group and 1 in peptic stricture group, requiring reoperation in 1. In the esophageal atresia group, there was 1 early distal stenosis requiring reoperation. In patients in which the distal esophagus was preserved (esophageal atresia and caustic stricture group), there were always signs of distal functional subobstruction, responding to dilatation in all but 1 patient. Gastroesophageal reflux was not a problem except for 1 patient with esophageal atresia, in whom the distal esophagus was resected because of ongoing distal obstruction with dilatation of the graft. Most patients eat and grow well, and respiratory problems were rare. CONCLUSION: Orthotopic jejunal pedicle graft reconstruction of the esophagus in children is a demanding operation with considerably morbidity but good long-term results.
机译:目的:重建儿童食道仍然是一个挑战。尽管空肠移植物保留了蠕动功能,但很少进行大范围的长期随访。我们希望在24名儿童中展示我们的经验。方法:在1988年至2005年期间,有24名儿童接受了原位空肠椎弓根移植入食管。 19例食管闭锁(18例无远端瘘管;除1例外,其余均进行了空肠移植),3例发生广泛性苛性狭窄,2例发生消化性狭窄。所有狭窄均已扩张许多次,消化道狭窄也已接受抗反流手术治疗。食管闭锁组的重建中位年龄为76天。该技术涉及右侧胸腔切开术,准备食道末端或切除患病食道。在剖腹手术中,准备了一个小小的有蒂的空肠移植物,并经皮下放置在右胸的原位。结果:所有患者均存活,并且没有移植物丢失。胸腔内漏5例,食管闭锁组4例,消化道狭窄组1例,需要再次手术。在食管闭锁组,早期远端狭窄1例需要再次手术。在保留了远端食管的患者中(食管闭锁和苛性狭窄组),总有远端功能性梗阻的迹象,除1例患者外,其余患者均对扩张做出反应。胃食管反流不是问题,除了1例食管闭锁患者,由于持续的远端阻塞和移植物扩张而切除了远端食道。大多数患者饮食和生长良好,呼吸系统疾病很少见。结论:小儿食管原位空肠椎弓根移植术是一项苛刻的手术,发病率较高,但长期效果良好。

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