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The role of community pharmacists in monitoring adverse drug reactions in Nigeria

机译:尼日利亚社区药师在监测药物不良反应中的作用

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Objectives: To identify the common types of adverse drug reactions (ADRs) detected and reported by community pharmacists in Nigeria. In addition we examined the extent of community pharmacists' involvement in ADR activities and evaluated the factors influencing community pharmacists' role in monitoring and reporting ADRs. Methods: The study was conducted among community pharmacists using a convenience sampling process. Verbal consent to participate in the study was sought during this initial contact. Structured and pre-tested questionnaires made up of closed and open-ended questions were given to the community pharmacists. Community pharmacists answered questions on demographics, the extent of their involvement in ADR activities, pharmacological class of drugs causing ADRs and number of ADRs detected and reported as well as the factors influencing their role in ADR activities. Key findings: Data were analysed using descriptive statistics and multiple regression analysis. The response rate for the study was 92.7%. The extent of involvement of community pharmacists in ADR activities was low. A total of 41cases of ADRs were identified and reported. Variables that were significant at P<0.05 and the study revealed that influences on community pharmacists' role in ADR activities were knowledge of ADRs (1.369), community pharmacists' experience (1.330) and patients' medical information (1.183). Conclusion: Analyses indicated that all classes of drugs examined, including herbal medicines, caused ADRs. This is contrary to the widely held view that herbal preparations are non-toxic in nature. Hence, this finding will elicit more interest in effective medication management and monitoring.
机译:目的:确定尼日利亚社区药剂师发现和报告的常见药物不良反应(ADR)类型。此外,我们检查了社区药师参与ADR活动的程度,并评估了影响社区药师在监测和报告ADR中作用的因素。方法:本研究是在社区药剂师中使用便利抽样程序进行的。在初次接触期间,寻求口头同意参加研究。将由封闭式和开放式问题组成的结构化和预先测试的调查表提供给社区药剂师。社区药师回答了有关人口统计学,他们参与ADR活动的程度,引起ADR的药理学类别以及检测和报告的ADR数量以及影响其在ADR活动中作用的因素的问题。主要发现:使用描述性统计和多元回归分析对数据进行分析。该研究的答复率为92.7%。社区药剂师参与ADR活动的程度很低。总共鉴定和报告了41例ADR。在P <0.05时具有显着性的变量,该研究表明,对社区药师在ADR活动中的作用的影响是对ADR的了解(1.369),社区药师的经验(1.330)和患者的医疗信息(1.183)。结论:分析表明,所检查的所有药物(包括草药)均引起ADR。这与人们普遍认为草药制品无毒的观点相反。因此,这一发现将引起对有效药物管理和监测的更多兴趣。

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