首页> 外文期刊>Journal of Pharmaceutical and Biomedical Analysis: An International Journal on All Drug-Related Topics in Pharmaceutical, Biomedical and Clinical Analysis >Assessing Jasminum grandiflorum L. authenticity by HPLC-DAD-ESI/MSn and effects on physiological enzymes and oxidative species
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Assessing Jasminum grandiflorum L. authenticity by HPLC-DAD-ESI/MSn and effects on physiological enzymes and oxidative species

机译:通过HPLC-DAD-ESI / MSn评估茉莉的真实性及其对生理酶和氧化性物质的影响

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摘要

The dried flower buds of Jasminum grandiflorum L. are widely consumed as infusion and used in traditional medicine for psychiatric disorders. It is important to have a well-established method for the chemical characterization of J. grandiflorum since there are resemblances with a toxic species, Gelsemium sempervirens (L.) Jaume Saint-Hilaire. HPLC-DAD-ESI/MSn analysis allowed identifying six phenolic compounds for the first time. Moreover, the evaluation of in vitro activity against central nervous system (CNS) related enzymes was undertaken for the first time, as well as against reactive species in order to support the efficacy towards CNS disorders.
机译:茉莉的干燥花芽作为输液被广泛食用,并被用于精神病的传统医学中。重要的是要有一个成熟的方法来鉴定大花菊的化学特性,因为它与有毒物种相似,即长臂猿(G.ems sempervirens(L.)Jaume Saint-Hilaire)。 HPLC-DAD-ESI / MSn分析允许首次鉴定出六种酚类化合物。此外,首次进行了针对中枢神经系统(CNS)相关酶以及针对反应性物种的体外活性评估,以支持针对CNS疾病的功效。

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