Middle cranial fossa arachnoid cysts (MFACs) are frequently asymptomatic. Here, we report the case of a 10-year-old boy with growth hormone deficiency (GHD) and an MFAC. His linear growth had followed the -2.5 SD line. On physical examination, his height was 120.8 cm (-2.6 SD), and the level of insulin-like growth factor 1 was low (87 ng/mL). GH provocative tests revealed GHD and brain magnetic resonance imaging (MRI) revealed an MFAC. We started treatment with GH replacement therapy (0.175 mg/kg/week). At the age of 12 years and 9 months, there were no interval changes in the features of the MFAC on the brain MRI. As his height was 145.5 cm (-1.7 SD) at the age of 13 years and 4 months, the therapy seems to be successful without sequelae. GH replacement therapy is suggested to be safe and effective to treat patients with GHD associated with arachnoid cysts.
展开▼
机译：颅中窝蛛网膜囊肿（MFAC）经常无症状。在这里，我们报道了一个10岁男孩患有生长激素缺乏症（GHD）和MFAC的病例。他的线性成长遵循-2.5 SD线。经身体检查，他的身高为120.8 cm（-2.6 SD），胰岛素样生长因子1的水平很低（87 ng / mL）。 GH激发试验显示GHD，而脑磁共振成像（MRI）显示MFAC。我们开始以GH替代疗法（0.175 mg / kg /周）进行治疗。在12岁零9个月大时，大脑MRI上MFAC的特征没有间隔变化。由于他在13岁零4个月大时身高为145.5厘米（-1.7 SD），因此治疗似乎很成功，没有后遗症。 GH替代疗法被认为是安全有效的治疗伴有蛛网膜囊肿的GHD患者。
展开▼
