Gaucher's disease (GD) is a rare but progressive lysosomal storage disorder caused by beta-glucocerebrosidase deficiency. Accordingly, glucocerebroside accumulates in the reticuloendothelial system and various musculo-skeletal complications (i.e., osteopenia, abnormal bone remodeling, delayed bone healing, pathological fracture, increased propensity for infection, and bleeding ensue due to involvement of the bone marrow). Likewise, in this report, we present a challenging case of GD that was accompanied by several of these skeletal complications including spondylodiscitis.
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