'Rescue' of bilateral subthalamic stimulation by bilateral pallidal stimulation: case report

摘要

Deep brain stimulation (DBS) of the. subthalamic nucleus (STN) or globus pallidus pars interna (GPi) is well established as a treatment for advanced Parkinson's disease. In general, one of the 2 targets is chosen based on the clinical features of each patient. Stimulation of both targets could be viewed as redundant, given that the 2 targets are directly connected. However, it is possible that each target has different mechanisms, with clinical effects mediated by orthodromic or antidromic stimulation.