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Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity.

机译:长的非编码RNA MALAT1衍生的mascRNA参与心血管先天免疫。

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摘要

Measurement of the serum concentration of insulin-like growth factor-I (IGF-l) is generally used as a screening investigation for disorders of the growth hormone (GH)/IGF-I axis in children and adolescents with short stature. IGF-I concentration is sensitive to short-term and chronic alterations in the nutritional state, and the interpretation of IGF-I measurements requires knowledge of the child's nutritional status. In this review, we summarize the effects of nutrition on the GH/IGF-I axis, and review the clinical implications of these interactions throughout childhood, both in under-nutrition and over-nutrition.
机译:胰岛素样生长因子-1(IGF-1)血清浓度的测量通常用作对身材矮小的儿童和青少年生长激素(GH)/ IGF-1轴异常的筛查研究。 IGF-I浓度对营养状态的短期和长期变化敏感,对IGF-I测量值的解释需要了解孩子的营养状况。在这篇综述中,我们总结了营养对GH / IGF-I轴的影响,并综述了这些相互作用在整个儿童时期的临床意义,包括营养不足和营养过度。

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