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RNA’s First Four Billion Years on Earth: A Biography

机译:RNA在地球上的前40亿年:传记

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DNA has long been the scientific superstar; now RNA is stealing the spotlight. Before there were bacteria, before there were archaea or eukaryotes, there were ribocytes—primitive replicating microbes that did all their biochemical maneuvering with RNA alone. “Ribocytes were likely cells because the most plausible way to maintain a coherent evolutionary identity is to be membrane delimited,” according to Michael Yarus, of the University of Colorado at Boulder. The limit-defining outer membrane of these simple creatures was probably made of cosmochemicals—“that is, amphipathic lipids [that] occur naturally and broadly in the universe and don’t require complex biosynthesis,” he explains. Such amphipathic lipids— fatty biomolecules with both water-friendly and -phobic regions that enable them to form bilayers in cell membranes—are still common today in the form of phospholipids.
机译:DNA一直以来都是科学巨星。现在RNA成为人们关注的焦点。在细菌出现之前,在古细菌或真核生物出现之前,就有核细胞-原始复制微生物,仅通过RNA即可完成所有的生化操作。科罗拉多大学博尔德分校的迈克尔·雅鲁斯(Michael Yarus)说:“核细胞很可能是细胞,因为维持相干进化身份最合理的方法是用膜定界。”他解释说,这些简单生物的极限外膜可能是由宇宙化学物质制成的,即“两亲性脂质[在自然界中广泛而自然地存在,不需要复杂的生物合成”。这类两亲性脂质(具有亲水和疏水区域的脂肪生物分子,使它们能够在细胞膜上形成双层)目前仍以磷脂形式存在。

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