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首页> 外文期刊>Journal of Medical Virology >Viral etiology of influenza-like illnesses during the influenza season between December 2011 and April 2012.
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Viral etiology of influenza-like illnesses during the influenza season between December 2011 and April 2012.

机译:在2011年12月至2012年4月的流感季节,流感样疾病的病毒病因学。

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摘要

The aim of this study was to determine the frequency of respiratory viruses responsible for respiratory tract infections in Turkish children during the 2011-2012 influenza season. Nasal swabs were obtained from patients with symptoms suggestive of an influenza-like illness between December 2011 and April 2012. Samples were analyzed with multiplex real-time polymerase chain reaction (RT-PCR) to help identify the causative viral pathogen. A total of 200 patients were enrolled in the study. A respiratory virus was detected successfully in 102 (51%) children; influenza A (H3N2) in 39.2%, influenza B in 23.5%, RSV in 15.6%, rhinovirus in 13.7%, bocavirus in 2.9%, coronavirus in 2.9%, and metapneumovirus in 0.9% of patients. Only one patient was co-infected with bocavirus and influenza A virus. A statistically significant difference in the mean age of presentation was observed between the various viral pathogens (P?
机译:这项研究的目的是确定2011-2012年流感季节土耳其儿童中引起呼吸道感染的呼吸道病毒频率。在2011年12月至2012年4月期间从症状似流感样症状的患者中获得鼻拭子。使用多重实时聚合酶链反应(RT-PCR)分析样品,以帮助鉴定病原性病毒病原体。该研究共招募了200名患者。在102名(51%)儿童中成功检测出呼吸道病毒;甲型流感(H3N2)占39.2%,乙型流感占23.5%,RSV占15.6%,鼻病毒占13.7%,博卡病毒占2.9%,冠状病毒占2.9%,偏肺炎病毒占0.9%。只有一名患者同时感染了博卡病毒和甲型流感病毒。在各种病毒病原体之间观察到平均呈报年龄有统计学差异(P <0.001)。 RSV患者明显更年轻,而感染流感病毒的儿童则明显更大。症状比较表明,与其他病毒组合相比,流感病毒发烧和头痛的发生率更高(P <0.001,<0.05)。在流感组中,发烧,咳嗽,鼻塞和鼻漏等症状的持续时间也明显更长(分别为P 0.001,<0.005,<0.001,<0.005)。人口统计分析表明,上学/日托出勤率是与流感感染风险显着增加相关的唯一参数。总体病毒病原体检出率为51%,本研究的结果表明,其他呼吸道病原体,无论是病毒性还是细菌性,也可能由于儿童的类流感样疾病而导致就诊。

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