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首页> 外文期刊>Journal of Medical Devices >Design of an Endonasal Graft Placement Tool for Repair of Skull Base Defects
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Design of an Endonasal Graft Placement Tool for Repair of Skull Base Defects

机译:修复颅底缺损的鼻内植骨植入工具的设计

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Endonasal skull base surgery (see Fig. 1) has proven to be a safe, effective, and significantly less invasive surgical approach when compared to open, highly invasive techniques [1]. Nevertheless, one initial difficulty with this minimally invasive approach has been postoperative leakage of cerebrospinal fluid (CSF) [2]. While the incidence of postoperative CSF leaks are low (<1%), the potential consequences are severe and include meningitis, brain abscess, neurologic deficits, brain hemorrhage, and death [1]. Depending on the nature of the surgery, violation of the skull base may be inevitable and is not uncommon during skull base surgery, regardless of the surgical approach. Several techniques for defect repair exist, but all are predicated on graft placement at the defect site (with the exception of the pedicled flap approach). It has been noted that, with current surgical tools, endonasal manipulation and placement of these grafts is difficult [2]. Endonasal graft placement is difficult for a variety of reasons. First, tool manipulability is severely limited by the narrow nasal passage; the surgeon's first challenge is maintaining control of the small graft (potentially as small as one mm) as the tool traverses from the nasal passage to the skull base defect. Further complicating the task of positioning this graft is the high variability in graft types (mucosa, bone, cartilage, or fascia [1]). Each of these grafts has varying rigidity, size, and thickness. Regardless of the graft's properties, the graft needs to be oriented in such a way that it optimally mates with the skull base defect to ensure full coverage or adequate fill, depending on the technique. The tools that are currently in use are either blunt instruments (with no gripping mechanism) that can be used to push the graft into place (with various curvatures) or graspers (forceps or grippers). Each of these tools has limitations; blunt instruments make holding the graft challenging as it traverses the nasal passages, and graspers make the simultaneous orienting of the graft and force application difficult. It is critical to note that these tools are not designed for endonasal graft placement. They are being used because, currently, there is no better solution.
机译:与开放的高侵入性技术相比,鼻内颅底手术(见图1)已被证明是一种安全,有效且侵入性较小的手术方法[1]。然而,这种微创方法的最初的困难是术后脑脊液(CSF)的泄漏[2]。术后脑脊液漏的发生率较低(<1%),但潜在的后果是严重的,包括脑膜炎,脑脓肿,神经功能缺损,脑出血和死亡[1]。根据手术的性质,在颅底手术期间,不可避免地会侵犯颅底,并且这种情况并不罕见,而与手术方法无关。存在几种修复缺陷的技术,但所有技术都基于将移植物放置在缺陷部位(带蒂皮瓣方法除外)。已经注意到,利用当前的手术工具,鼻内操纵和这些移植物的放置是困难的[2]。出于各种原因,鼻内移植物放置困难。首先,狭窄的鼻腔通道严重限制了工具的可操作性。当工具从鼻腔通道穿过到颅底缺损时,外科医生的第一个挑战是保持对小型移植物的控制(可能小至一毫米)。使该移植物定位的任务进一步复杂化的是移植物类型(粘膜,骨骼,软骨或筋膜[1])的高变异性。这些移植物中的每一个都具有不同的刚度,大小和厚度。不管移植物的性质如何,移植物的取向都必须使其与颅底缺损最佳匹配,以确保完全覆盖或充分填充,具体取决于技术。当前使用的工具是可用于将移植物推入到位(具有不同曲率)的钝器(无夹持机构)或抓紧器(钳子或抓紧器)。这些工具都有其局限性。钝器使穿过鼻腔的移植物难以通过鼻夹,而抓紧器使移植物的同时定向和施力变得困难。重要的是要注意,这些工具并非为植入鼻内支架而设计。之所以使用它们,是因为目前没有更好的解决方案。

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