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Clinical features of abdominal actinomycosis: a 15-year experience of a single institute.

机译:腹部放线菌病的临床特征:一家机构的15年经验。

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摘要

This study was designed to evaluate the clinical features of abdominal actinomycosis and to assess its therapeutic outcome. We reviewed patients with abdominal actinomycosis in Seoul St. Mary hospital, between January 1994 and January 2010. Twenty-three patients (5 male and 18 female, mean age, 47.8 yr; range, 6-75 yr), with abdominal actinomycosis were included. Emergency surgery was performed in 50% due to symptoms of peritonitis. The common presentation on preoperative computerized tomography was a mass with abscess, mimicking malignancy. The mean tumor size was 7.0 cm (range, 2.5-10.5). In all patients, actinomycotic masses were surgically removed. Mean duration of hospital stay was 17.8 days (range, 5-49). Long term oral antibiotic treatment (mean 4.2 months; range, 0.5-7.0 months) were administered to all patients. All patients were free of recurrence after a median follow up of 30.0 months (mean 35.5 +/- 14.8 months, range, 10.0-70.0 months); recurrence was not seen in any patient. In conclusion, abdominal actinomycosis should be included as a differential diagnosis when an unusual abdominal mass or abscess presents on abdominal CT. Assertive removal of necrotic tissue with surgical drainage and long term antibiotic treatment provide a good prognosis in patients with actinomycosis.
机译:本研究旨在评估腹部放线菌病的临床特征并评估其治疗效果。我们回顾了1994年1月至2010年1月在首尔圣玛丽医院接受腹部放线菌病治疗的患者。其中包括腹部放线菌病的23例患者(男5例,女18例,平均年龄47.8岁;范围6-75岁)。 。由于腹膜炎的症状,进行急诊手术的比例为50%。术前计算机断层扫描的常见表现是脓肿,模仿恶性肿瘤。平均肿瘤大小为7.0 cm(范围2.5-10.5)。在所有患者中,都通过手术切除了放线菌肿块。平均住院时间为17.8天(范围5-49)。所有患者均接受长期口服抗生素治疗(平均4.2个月;范围0.5-7.0个月)。中位随访30.0个月(平均35.5 +/- 14.8个月,范围10.0-70.0个月)后,所有患者均未复发。任何患者均未见复发。总之,当腹部CT出现异常腹部肿块或脓肿时,应包括腹部放线菌病作为鉴别诊断。对于放线菌病患者,通过手术引流和长期抗生素治疗来主动清除坏死组织可提供良好的预后。

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