A Study on Bioactive Surface Modification of Biomedical Ti-based Alloys

摘要

Ti and Ti-based alloys have been widely used for the biomedical applications due to their superiorities of biocompatibility, mechanical properties and corrosion resistance. However, there has been the limiting factor for these metals to show the low affinity to the living bone. The purpose of this study is to improve the bone-bonding ability between Ti-base alloys and living bone through the chemically activated process and thermally activated one. After those treatments, the effects of the pre-treatments on the bonding property were evaluated by in vitro test. Two kinds of Ti-based alloys, Ti-In-Nb-Ta and Ti-6Al-4V, were used in this study. These specimens were alkali treated in 5.0M NaOH solution and heat treated in vacuum furnace at 600 deg C and soaked in SBF (simulated body fluid ) including nearly same ion concentration as human blood plasma. The microstructural changes of activated surface were observed by OM, SEM, EDS, XRD, and AES. Two surface modified alloys showed improved bioactive behavior. And Ti-In-Nb-Ta had the better bioactivity than Ti-6Al-4V in SBF.