ACCESS TO REMOTELY CONTROLLED PRODUCTION OF ~86Y USING AQUEOUS TARGET MATRICES AS ALTERNATIVE TO SOLID STATE TARGETRY

摘要

In the recent years other - mostly metallic - radionuclides for PET gained more and more interest. However, for production of these alternative positron emitters the vast majority of them affords solid targets in form of metal foils, oxide or salt pellets [1, 2] which can not be operated by an automated processing. The disadvantages are: 1~st, manual cyclotron intervention is practically unsuited for daily routine radionuclide production and 2nd the operating staff receives high radiation doses from the activated target. An alternative could be the irradiation of aqueous salts of target isotopes, allowing automated target operation. The major requirements are: I.) thermal stability of the dissolved compound, II.) avoidance of counter ions containing nuclides which produce long-lived radionuclides under irradiation and III.) high solubility of the salt in the aqueous matrix. Here we report the possibility of this alternative radionuclide production concept by production of ~86Y (cf. [3,4]), generated by irradiation of strontium nitrate dissolved in water.