High specific activity tritium labeling of anti-tumor agent CEP-2563

Judith A. Egan; Crist N. Filer; Robert L. Hudkins

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High specific activity tritium labeling of anti-tumor agent CEP-2563

机译：高比活度tri标记的抗肿瘤药CEP-2563

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[Ester Methylene-~3H] CEP-2563 (9) was synthesized by the tritiation of precursor 6 with NaB~3H_4 followed by esterification with BOC-Lys(BOC)-beta-Ala-OH and deprotection.

机译：[酯亚甲基〜3H] CEP-2563（9）的合成方法是：将前体6用NaB〜3H_4 tri化，然后用BOC-Lys（BOC）-β-Ala-OH酯化并脱保护。

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《Journal of Labelled Compounds and Radiopharmaceuticals》 |2005年第13期|共5页
作者
Judith A. Egan; Crist N. Filer; Robert L. Hudkins;
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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
anti-tumor; CEP-751; CEP-2563; NaB~3H_4; tritium;

机译：抗肿瘤;CEP-751;CEP-2563;NaB〜3H_4;t;

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1. High specific activity tritium labeling of anti-tumor agent CEP-2563 [J] . Judith A. Egan, Crist N. Filer, Robert L. Hudkins Journal of Labelled Compounds and Radiopharmaceuticals . 2005,第13期

机译：高比活度tri标记的抗肿瘤药CEP-2563
2. Synthesis of tritium-labeled cyadox, a promising antimicrobial growth-promoting agent with high specific activity [J] . Harnud Sechenchogt, Zhang Aiqun, Yuan Zonghui Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine . 2018,第期

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3. Potent antiviral agent WIN 54954: high specific activity labelling with tritium. [J] . Egan JA, Nugent RP, Filer CN Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine . 2004,第6期

机译：高效抗病毒药WIN 54954：高high标记活性。
4. RAPID SYNTHESIS OF HIGH SPECIFIC ACTIVITY TRITIUM-LABELED ANTIBIOTICS [C] . Scot Pounds International Symposium on the Synthesis and Applications of Isotopes and Isotopically Labelled Compounds . 2004

机译：快速合成高比活性氚标记的抗生素
5. Design and mechanistic studies of low reduction potential specific anti-tumor agents. [D] . Lemus, Robert Huerta. 1990

机译：低还原潜力的特定抗肿瘤药物的设计和机理研究。
6. Potent antiviral agent WIN 54954: high specific activity labelling with tritium [O] . Judith A. Egan, Richard P. Nugent, Crist N. Filer -1

机译：高效抗病毒剂WIN 54954：高specific标记活性
7. High specific activity tritium-labeled N-(2-methoxybenzyl)-2,5-dimethoxy-4-iodophenethylamine (INBMeO): A high-affinity 5-HT2A receptor-selective agonist radioligand [O] . David E. Nichols, Stewart P. Frescas, Benjamin R. Chemel, 2008

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High specific activity tritium labeling of anti-tumor agent CEP-2563

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