Synthesis of Indeno[1,2-d]pyrimidin-5-Ones and Their Fluorescence in Solid State

摘要

New fluorescent compounds, 2-substituted indeno[1,2-d]pyrimidin-5-ones (3a, 3b, 3c, 3d) were synthesized in good yield by the reaction of 2-[bis(methylsulfanyl)methylene]indan-1,3-dione (1) with the respective amidine derivatives [guanidine carbonate (2a), acetamidine hydrochloride (2b), S-methylisothiourea sulfate (2c), and S-benzylisothiourea sulfate (2d)]. 4-Substituted amino-2-aminoindeno[1,2-d]pyrimidin-5-ones (7b, 7c, 7d) were synthesized by a one-pot reaction of 1, 2a and the respective amine compounds (4b, 4c, 4d) in pyridine. These fused pyrimidine derivatives showed fluorescence in the solid state.