F-18-NaF and F-18-FDG PET/CT in Gorham-Stout Disease

摘要

Gorham-Stout disease (GSD) is an extremely- rare skeletal disorder of unknown etiology characterized by benign proliferation of vascular or lymphatic channels, leading to progressive bone resorption. We report on a patient diagnosed with GSD affecting the right scapula and the right ribs, who underwent PET/CT scans using F-18-FDG and F-18-NaF. The remnant upper portion of the affected scapula did not Show F-18-FDG uptake but demonstrated markedly increased demon F-18-NaF activity Furthermore, intense F-18-NaF activity was seen on the right posterior ribs, which were actively being re sorbed, suggesting the potential application of F-18-NaF-PET/CT imaging in GSD diagnosis and follow-up.