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The impact of NICE (UK) recommendations on outcomes of cardiac pacemaker implantations - A single-centre, district hospital experience

机译:NICE(UK)建议对心脏起搏器植入结果的影响-单中心地区医院的经验

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Aims The National Institute for Health and Clinical Excellence (NICE) recommends the use of dual-chamber pacemakers for all patients with bradycardia with a few exceptions. We aimed to evaluate our compliance to the guidelines and the implications of different pacing modalities on follow-up outcomes. Methods We conducted two retrospective studies involving a total of 316 patients. The first study conducted over a 36-month period examined our performance prior to the introduction of the NICE guidance. The more recent second study conducted over a 12-month period examined our compliance to the NICE guidance upon its introduction and adoption. Data were analysed in separate groups according to pacemaker types. Symptom control and mortality were measures on follow-up outcomes. Results Our compliance to the guidance increased from 72% in the former study to 78% in the latter study (P = 0.17). Symptom control and mortality were not significantly different between the two studies. Combining both studies, fewer NICE-compliant patients complained of persisting symptoms after 1 year (P = 0.36). Although fewer deaths were observed in the compliant group, this again was not statistically significant (P = 0.10). Although age was not a criteria in selecting a device, younger patients were more likely to receive a pacemaker according to NICE recommendations (P = 0.001). Conclusions We achieved a near 80% level of compliance to NICE guidance. Our non-NICE-compliant patients did not have a poorer outcome than those who were compliant. The decision to insert single- or dual-chamber pacemakers is often multifactorial and individual doctors may have different practices.
机译:目的美国国家卫生与临床卓越研究所(NICE)建议对所有心动过缓患者使用双腔起搏器,除少数例外。我们旨在评估我们对指南的遵守情况以及不同起搏方式对后续结果的影响。方法我们进行了两项回顾性研究,涉及316名患者。在引入NICE指南之前,历时36个月的第一项研究检查了我们的表现。最近12个月进行的第二项研究检查了我们对NICE指南的引入和采用是否遵守。根据起搏器类型将数据分为不同的组。症状控制和死亡率是随访结果的指标。结果我们对指导的依从率从前一项研究的72%增加到了后者的78%(P = 0.17)。两项研究之间的症状控制和死亡率无显着差异。结合两项研究,较少的NICE依从性患者在1年后抱怨症状持续(P = 0.36)。尽管在依从组中观察到较少的死亡,但这再次没有统计学意义(P = 0.10)。尽管年龄不是选择设备的标准,但根据NICE的建议,年轻患者更可能接受起搏器(P = 0.001)。结论我们达到了NICE指南的近80%的遵从性。我们的非NICE依从性患者没有比依从性较差的结果。插入单腔或双腔起搏器的决定通常是多因素的,个别医生的做法可能有所不同。

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