Study the Nature and Potentiation of Immune Response of Tetanus Toxoid

摘要

ABSTRACT:Immunoglobulin play an essential role in the body's immune system.The present study was designed to determined the antibodies [ IgM, IgG and IgG (T) ] against immunomodulators tetanus toxoid vaccine and ultracorn, in the serum horse. Twelve draughting horses of both sexes with average age of 4-6 years and 250 kg weight were used throughout the experiment. Horses were divided into four groups as follows: The first control group represented ( horses not received any vaccine or immunomodulators ) ; The second horses were injected I.M with 6ml of 60 LF purified concentrated tetanus toxoid vaccine and reinjected with same dose 6 weeks later. The third were injected S.C with 6 ml ultracorn and reinjected with same dose 6 weeks later. The fourth group horses were injected I.M. with 6 ml of 60 LF tetanus adsorbed toxoid vaccine simultaneously with S.C. injection of 6ml ultracorn.