Case Reports: Novel Use of 308-nm Excimer Laser to Treat a Primary Cutaneous CD30+ Lymphoproliferative Nodule

摘要

CD30+ cutaneous lymphoproliferative disorders (CLPDs) are the second most common cutaneous T-cell lymphoma (CTCLs) after mycosis fungoides (MF), constituting approximately 25% of CTCL cases.1-2 The CD30 antigen is a member of the tumor necrosis factor receptor family and may be expressed on activated B and T cells.2 CD30+ CLPDs represent a spectrum of disorders ranging from lymphomatoid papulosis to borderline CD30+ lesions to anaplastic large-cell lymphoma (ALCL). CD30+ CLPDs occur at all ages, but peak incidence is in the fifth and sixth decades of life and are more prevalent in males.1-2 We describe a patient with a solitary cutaneous CD30+ lymphoproliferative nodule that was successfully treated with a 308-nm excimer laser (XTRAC Model AL7000 Excimer Laser; PhotoMedex, Montgomeryville, PA).