Combined topical delivery and dermalinfusion of decapeptide-12 accelerates resolution of post-inflammatory hyperpigmentation in skin of color

摘要

The combined use of topical delivery and dermalinfusion~R of decapeptide-12 represents a novel, safe, and efficacious noninvasive approach to achieve accelerated resolution of postinflammatory hyperpigmentation (PIH), an especially difficult to treat and common dermatoses in skin of color.SilkPeel~R is a device that abrades the stratum corneum using a diamond-encrusted handpiece while simultaneously delivering a topical solution into the epidermis under pneumatic pressure. Primary indications for SilkPeel procedures include dry skin, acne, hyperpigmentation, and other derma-tologic indications. Desai and Moy also described successful treatment of erythematotelangectatic and papulopustular ro-sacea with SilkPeel dermalinfusion.